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Horm Metab Res 1971; 3(5): 318-320
DOI: 10.1055/s-0028-1094134
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© Georg Thieme Verlag KG Stuttgart · New York

Growth Hormone Response to Rapid Intravenous Injection of Various Amounts of β1-24 ACTH

O. D. Bruno , G.  Copinschi , R.  Leclercq
  • Laboratoires de Physiopathologie, de Médecine Expérimentale et de Chimie Clinique, et Clinique Médicale, Hôpital Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Plasma levels of immunoreactive human growth hormone (HGH) and of Cortisol were measured in normal subjects after intravenous injection of 600 ng, 50 µg and 1.0 mg of β1-24 ACTH. All doses elicited normal Cortisol responses. There was no increment in plasma HGH following injection of the lowest two doses; variable HGH responses were observed after injection of 1.0 mg. These data do not support the hypothesis that corticotrophin could mediate HGH release in stress situations.

Key words

Plasma Cortisol - Plasma Sugar - HGH Release - Corticotrophin Tests

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