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Horm Metab Res 1971; 3(1): 52-54
DOI: 10.1055/s-0028-1095028
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© Georg Thieme Verlag KG Stuttgart · New York

The Erythrogenic Effect of Steroids with Predominant Anabolic or Androgenic Activity in the Polycythemic Mouse[*]

C. E. Bozzini [**] , R. M. Alippi
  • Cátedra de Fisiología, Facultad de Odontología, Universidad de Buenos Aires;
    and Departamento de Radiobiología, Comision Nacional de Energía Atómica, Buenos Aires, Argentina
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

The erythropoietic effect of testosterone propionate and caproate, androstanolone, nandrolone phenylpropionate and decanoate, and oxymetholone were compared in polvcytemic mice. Erythropoiesis, as measured by the 59Fe incorporation into newly-formed red cells, was markedly stimulated by all injected steroids. It is remarkable that all of them produced similar stimulation of red cell production, regardless whether they were predominantly anabolic or androgenic. These results suggest that the erythrogenic activity of the above steroids is independent of their virilizing or myotrophic effects.

Key words

Erythropoiesis - Androgens - Steroids - Anabolic Steroids

1 This work was partially supported by grant no. 1126e from the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina

1 This work was partially supported by grant no. 1126e from the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina

2 Established Investigator, Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina

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