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Planta Med 1978; 33(4): 356-359
DOI: 10.1055/s-0028-1097391
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Cytostatic Activity of Sesquiterpene Lactones from Compositae of the Canary Islands

A. G. Gonzalez1 , V. Darias1 , G. Alonso2 , J. N. Boada1 , M. Feria1
  • 1Instituto de Productos Naturales Orgânicos, CSIC, Tenerife.
  • 2Instituto Quimica Médica, CSIC, Madrid, Spain.
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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

The cytostatic properties of a series of fifteen lactones from some Compositae collected in the Canary Islands were examined. Nine of these lactones were isolated for the first time in the Instituto de Productos Naturales Organicos of Tenerife. It would seem that an α–methylene–γ–lactone grouping in the molecule is essential for cytotoxic activity.

Key Word Index

Compositae - Sesquiterpene Lactones - Cytostatic Activity

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