Application of intralesional traction assistance with traction wire to endoscopic submucosal dissection for colorectal neoplasms

Endoscopic submucosal dissection (ESD) is commonly performed for large colorectal neoplasms as a local treatment [1]. Several assistive traction methods have been developed to overcome the technical difficulties of ESD [2] [3] [4] [5]. We present a case of colorectal neoplasm that was successfully treated with intralesional traction-assisted ESD using a novel traction device ([Fig. 1]). This device, which consists of two clips equipped with a half-moon-shaped memory traction wire, allows a clear view of the submucosal layer by elevating the lesion with the shape memory force of the wire.

Fig. 1 Traction wire.

A 60-year-old woman with ulcerative colitis in remission had a sporadic lateral spreading tumor measuring 35 mm in the transverse colon. Intralesional traction-assisted ESD was performed on the lesion ([Video 1]). Marking dots were created around the lesion. Submucosal injection and mucosal incision were performed outside the marking dots ([Fig. 2 a]). After completing the circumferential mucosal incision, the first clip with a half-moon-shaped memory wire was placed at the anal margin of the lesion ([Fig. 2 b]). The second clip that hooked and stretched the wire was then placed at the oral margin of the lesion ([Fig. 2 c, d]). Sufficient intralesional traction was achieved by lifting the anal mucosal flap with the force generated by the shape memory effects of the wire ([Fig. 2 e]). A clear view of the submucosal layer was achieved for dissection, without any complications until en bloc resection was completed ([Fig. 2 f]). The resected specimen was retrieved by grasping the wire using forceps.

Video 1 Application of intralesional traction assistance with traction wire to endoscopic submucosal dissection for colorectal neoplasms.

Fig. 2 Schemata showing each step of the intralesional traction technique using traction wire in colorectal endoscopic submucosal dissection. a Circumferential mucosal incision around the lesion. b First clip with traction wire placed at the anal margin of the lesion. c The wire hooked by the second clip. d The second clip placed at the oral margin of the lesion. e Adequate intralesional traction. f A clear view of submucosal layer for submucosal dissection.

One advantage of intralesional traction-assisted ESD is that it can be applied to lesions in any colonic location because sufficient traction can be created within the target lesion. Secondly, this traction device does not interfere with endoscope manipulation. Intralesional traction-assisted ESD could be a promising option for the treatment of colorectal neoplasms.

Endoscopy_UCTN_Code_CPL_1AJ_2AD

Competing interests

Prodi GI traction wire was provided by Covidien Japan Inc. free of charge. Eikichi Ihara participated in the funded research of Takeda Pharmaceutical Co., Ltd. and belongs to the endowed course supported by the companies mentioned, including Ono Pharmaceutical Co., Ltd., Miyarisan Pharmaceutical Co. Ltd., Sanwa Kagaku Kenkyusho Co., Ltd., Otsuka Pharmaceutical Factory, Inc., Fujifilm Medical Co., Ltd., Termo Corporation, Fancl Corporation, Ohga Pharmacy, and Abbott Japan, LLC. Eikichi Ihara received a lecture fee from Takeda Pharmaceutical Co.

• References

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• 2 Inoue K, Yoshida N, Dohi O. et al. Effects of the combined use of a scissor-type knife and traction clip on endoscopic submucosal dissection of colorectal tumors: a propensity score-matched analysis. Endosc Int Open 2021; 9: E1617-E1626 DOI: 10.1055/a-1535-0786.
• 3 Suzuki Y, Tanuma T, Nojima M. et al. Comparison of dissection speed during colorectal ESD between the novel Multiloop (M-loop) traction method and ESD methods without traction. Endosc Int Open 2020; 8: E840-E847 DOI: 10.1055/a-1161-8596.
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Publication History

Article published online:
14 April 2022