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DOI: 10.1055/s-0038-1639728
A rare differential diagnosis of subglottic stenosis
Introduction:
Primary involvement of the larynx in non-Hodgkin's lymphoma (NHL) is rare. They represent < 1% of all laryngeal tumors. Usually laryngeal NHL occurs in the supraglottic area sometimes compared with infiltration of the glottic part. Primary involvement of the subglottic region is rarely reported.
Case-report:
A 29-year-old man was presenting with exertional dyspnea, exertional stridor and dysphonia in our hospital. He suffered from these symptoms existed since two months without B symptoms. He got 250 mg prednisolone intravenously in case of suspected subglottic stenosis in another hospital, but symptoms didn't change. A CT scan of the neck and thorax revealed a small hyperplasia of the soft tissue in the subglottic region (right > left). In the clinical examination vocal cords appeared grey with a smooth surface, freely movable with suspicious additional subglottic tissue. For further diagnostics tracheobronchoscopy and laryngoscopy were performed under general anesthesia. On both sides of the subglottic area suspicious mucosa appeared. A biopsy was taken.
Results:
The histological examination verified a lymphoid cell population with active proliferation. Subglottic manifestation of B-cell lymphoma or acute lymphoblastic leukemia seems to be possible.
Conclusion:
This case-presentation should to draw attention to rare differential diagnosis of subglottic stenosis. Beside ENT- and internistic diseases we should also think of haematological reasons.
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No conflict of interest has been declared by the author(s).
Publication History
Publication Date:
18 April 2018 (online)
© 2018. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Stuttgart · New York