Pneumologie 2019; 73(S 01)
DOI: 10.1055/s-0039-1678132
Freie Vorträge (FV DGP 7) – Sektion Klinische Pneumologie
Hot topics der klinischen Pneumologie
Georg Thieme Verlag KG Stuttgart · New York

Compliance to respiratory and non-respiratory medication in patients with COPD: results of the German COPD cohort COSYCONET

N Königsdorfer
1   Klinikum der Universität München
,
K Kahnert
2   Department of Internal Medicine V, Respiratory Medicine and Thoracic Oncology, Thoracic Oncology Centre Munich, Ludwig-Maximilians-Universität München, Member of the German Center for Lung Research (Dzl Cpc-M)
,
S Söhler
3   Philipps-Universität Marburg
,
T Welte
4   Medizinische Hochschule Hannover, Klinik für Pneumologie
,
J Behr
5   Klinikum der LMU München, Medizinische Klinik und Poliklinik V, Comprehensive Pneumology Center
,
JH Ficker
6   Klinikum Nürnberg Südmedizinische Klinik 3, Med. Klinik 3, Paracelsus Medizinische Privatuniversität Nürnberg
,
R Bals
7   Klinik für Innere Medizin V, Universitätsklinikum des Saarlandes
,
H Watz
8   Pneumologisches Forschungsinstitut an der Lungenclinic Grosshansdorf
,
J Lutter
9   Helmholtz Zentrum München, Institut für Gesundheitsökonomie und Management Im Gesundheitswesen, Comprehensive Pneumology Center Munich (Cpc-M), Mitglied des Deutschen Zentrums für Lungenforschung (Dzl)
,
T Lucke
1   Klinikum der Universität München
,
F Biertz
10   Hannover Medical School
,
P Alter
11   Universitätsklinikum Gießen und Marburg, Standort Marburg, Innere Medizin, Sp Pneumologie
,
C Vogelmeier
12   Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Phillips-University Marburg, Member of the German Centre for Lung Research (Dzl)
,
RA Jörres
13   Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin, Klinikum der Universität München, LMU München
› Author Affiliations
Further Information

Publication History

Publication Date:
19 February 2019 (online)

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    Adherence to COPD medication is often considered to be lower than in other chronic diseases. To achieve comparability we analysed the intake of all medication in the same patients with COPD and frequent comorbidities.

    Within the COPD cohort COSYCONET we contacted 1042 patients of GOLD grades 0 – 4, mailing them a list with all medication regarding all their diseases, asking for regular, irregular and non-intake.

    Valid responses were obtained in 809 patients covering a wide spectrum of drugs. Intake of LABA, LAMA or ICS was regular in 90.9% of patients, even higher for cardiovascular and anti-diabetes medication but lower for hyperlipidemia and depression/anxiety medication. Regular intake of respiratory medication did not depend on GOLD groups A – D or grades 1 – 4, highest in patients with concomitant cardiovascular disorders and lowest for concomitant asthma. It was larger for LAMA and LABA administered via combined compared to single inhalers, and lower when similar compounds were prescribed twice. Most differences did not reach statistical significance owing to the overall high adherence.

    Our results indicate a high adherence to respiratory medication in participants of a COPD cohort, especially in those with cardiovascular comorbidities. This observation suggests room for educational strategies for improvement.


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