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DOI: 10.1055/s-0039-1681289
GERMAN ESD REGISTRY – FIRST RESULTS
Publication History
Publication Date:
18 March 2019 (online)
Aims:
In Europe, endoscopic submucosal dissection (ESD) is not yet the standard treatment for premalignant or early malignant lesions in the gastrointestinal (GI)-tract. High quality data is limited to single center studies. In this study, we present the first results of the German ESD registry which was set up to evaluate and assess the technical success, curative resection rate, economic aspects as well as long term outcomes of ESD procedures performed in Germany.
Methods:
The German ESD registry study is a prospective, multicenter trial. Management and evaluation of collected data is done in a central data base at Klinikum Augsburg, Germany. Data is collected anonymously via electronic case report form (CRF).
Results:
In the year 2017, 18 hospitals included a total amount of 381 ESDs. A total of 139 resected lesions were located in the rectum, 109 lesions in the esophagus, 105 lesions in the stomach, 26 lesions in the colon and 2 lesions in the duodenum.
An overall en bloc resection rate of 94 percent was achieved; the highest en bloc rate was in the esophagus with 98% and the lowest en bloc rate in the colon with 88%.
The overall histological R0 resection rate was 81%; the highest R0-Rate was in the rectum (88%) and the lowest in the colon (73%). The overall complication rate was 15%; when colonic- ESDs were excluded, the complication rate dropped to 8,5%.
Conclusions:
A total of 381 ESD procedures were registered in 2017 with favourable R0 resection and complication rates. The German ESD registry represents a first step towards establishing ESD as a standard treatment of choice for premalignant und early malignant lesions. However, colonic ESD still remains a hurdle for western endoscopists. Further data collection and data analysis in 2018 will help to expand on the results shown here.
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