Diabetologie und Stoffwechsel 2019; 14(S 01): S11-S12
DOI: 10.1055/s-0039-1688137
ePoster
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Georg Thieme Verlag KG Stuttgart · New York

A meta-analysis of pharmaceutical care components for diabetes patients

MA Deters
1   Heinrich-Heine-University Duesseldorf, Institute of Clinical Pharmacy and Pharmacotherapy, Düsseldorf, Germany
,
A Laven
1   Heinrich-Heine-University Duesseldorf, Institute of Clinical Pharmacy and Pharmacotherapy, Düsseldorf, Germany
,
A Castejon
2   Department of Pharmaceutical Sciences, College of Pharmacy, University of Fort Lauderdale, Fort Lauderdale, United States
,
W Doucette
3   College of Pharmacy, University of Iowa, Division of Clinical and Administrative Pharmacy, Iowa, United States
,
L da Slveira Ev
4   University of Ouro Preto, Department of Pharmacy, Ouro Preto, Brazil
,
I Krass
5   The University of Sydney, Pharmacy Practice, Sydney, Australia
,
E Mehuys
6   Faculty of Pharmaceutical Sciences, Department of Bioanalytics, Ghent, Belgium
,
E Obarcanin
7   Institute of Clinical Pharmacy and Pharmacotherapy, Pharmacy and Pharmacotherapy, Düsseldorf, Germany
,
H Schwender
8   Mathematisches Institut der Heinrich-Heine-Universität, Düsseldorf, Germany
,
S Läer
7   Institute of Clinical Pharmacy and Pharmacotherapy, Pharmacy and Pharmacotherapy, Düsseldorf, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
07 May 2019 (online)

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    Objective:

    The objective of the systematic literature research and meta-analysis were the evaluation of randomised controlled trials (RCTs) that included interventions provided by community pharmacists with diabetes patients. Also, the components used in interventions were analysed.

    Method:

    The literature research was conducted in PubMed and Cochrane Central Register of Controlled Trials (January 2000 to April 2016). RCTs containing pharmaceutical care for diabetes patients conducted by community pharmacists were included. Corresponding authors of the eligible studies were contacted to obtain detailed information about intervention and training data. The received information was analysed. The meta-analysis for continuous outcomes was conducted using the random effect model. Missing and incomplete data were excluded according to the publications of the analysed studies. Statistical analyses were done with R.

    Results:

    Eleven studies were eligible for further analysis and corresponding authors of six studies responded to our request sending their data. The calculated meta-analytical effect of all 640 analysed patients was a HbA1c-difference of -0.66% with a 95% confidence interval of -0.86 to -0.45%. The analysis revealed that most intervention elements had a significant positive meta-analytical effect on the HbA1c-values of the diabetes patients. Most effective were patient-centred and multidisciplinary intervention components.

    Conclusion:

    Our meta-analysis suggests, that interventions led by community pharmacists in addition to standard of care can improve glycaemic control in patients with diabetes mellitus. According to the analysis pharmaceutical care should include structured multidisciplinary collaboration, joint decision-making, medication reviews and the assessment of patients' health beliefs and medication knowledge.


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