Endoscopy 2020; 52(S 01): S41
DOI: 10.1055/s-0040-1704128
ESGE Days 2020 oral presentations
Thursday, April 23, 2020 10:30 – 12:00 Innocent & guilty polyps Wicklow Meeting Room 3
© Georg Thieme Verlag KG Stuttgart · New York

IMPACT OF SECOND GENERATION ENDOCUFF-ASSISTED COLONOSCOPY VS. STANDARD COLONOSCOPY ON ADENOMA DETECTION RATE IN ROUTINE PRACTICE: A CLUSTER-RANDOMIZED CROSSOVER TRIAL

D Karsenti
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
G Tharsis
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
B Perrot
2   Université de Nantes, Université de Tours, Institut de Recherche en Santé (IRS2), Methodology Unit, UMR INSERM 1246 SPHERE, Nantes, France
,
P Cattan
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
G Tordjman
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
F Venezia
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
E Zrihen
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
D Gillot
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
A Gillet
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
C Hagege
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
J Samama
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
I Etienney
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
JP Lab
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
B Guigui
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
J Zago
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
B Benkhessou
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
P Burtin
3   Institut Gustave Roussy, Villejuif, France
,
M Cavicchi
1   Clinique Paris-Bercy, Endoscopy Unit, Charenton-Le-Pont, France
,
PD Paris-Bercy
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

 
 

    Aims Endocuff vision (ECV) is the second generation of a recent device designed to improve polyp detection. The aim of this study was to evaluate the impact of ECV on adenoma detection rate (ADR) in routine colonoscopy.

    Methods This cluster-randomized crossover trial compared endocuff-assisted (ECV+) to standard (ECV-) colonoscopy. Two teams of 11 endoscopists each were formed. They were balanced in terms of basal ADR, gender and volume of activity. The team that started with ECV+ was selected based on randomization. Once half the inclusions had been treated, a switch was made and the other team performed ECV+. The main criterion was ADR.

    Results 2,058 patients were included (1,032 ECV- vs. 1,026 ECV+). Both groups were comparable. Taking into account the cluster crossover design, we observed a 9.8% [5.7;13.8] increase in ADR in the ECV+ group (29.4% vs. 39.2%, P < 0.001), mostly when polyps < 1 cm.

    Regarding the physicians’ basal ADR, the only significant increase was observed in the “good detectors” group (31% vs. 41%, P < 0.001), but there was no significant increase in the “bad detectors” group (24% vs. 30%, P=0.11). ECV had a positive impact in all colonic sectors, except the rectum. Cecal intubation time was significantly lower with ECV (P < 0.001). No complication due to ECV were reported in this study.

    Conclusions We observed a significant increase of approximately 10% in ADR in the ECV+ group. ECV had a very significant positive impact in the “good detectors”, but not in the “bad detectors”.

    Trial registered at ClinicalTrials.gov (NCT03344055).


    #