Endoscopy 2020; 52(S 01): S50
DOI: 10.1055/s-0040-1704155
ESGE Days 2020 oral presentations
Thursday, April 23, 2020 14:30 – 16:00 Polyp forensics: Colon advanced Wicklow Meeting Room 3 Imaging 2
© Georg Thieme Verlag KG Stuttgart · New York

COLON POLYP DETECTION USING LINKED COLOR IMAGING COMPARED TO WHITE LIGHT IMAGING: A SYSTEMATIC REVIEW AND META-ANALYSIS

S Shinozaki
1   Shinozaki Medical Clinic, Utsunomiya, Japan
2   Jichi Medical University, Gastroenterology, Shimotsuke, Japan
,
Y Kobayashi
2   Jichi Medical University, Gastroenterology, Shimotsuke, Japan
,
Y Hayashi
2   Jichi Medical University, Gastroenterology, Shimotsuke, Japan
,
H Sakamoto
2   Jichi Medical University, Gastroenterology, Shimotsuke, Japan
,
K Sunada
2   Jichi Medical University, Gastroenterology, Shimotsuke, Japan
,
A Lefor
3   Jichi Medical University, Surgery, Shimotsuke, Japan
,
H Yamamoto
2   Jichi Medical University, Gastroenterology, Shimotsuke, Japan
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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    Aims Linked color imaging (LCI) is a novel image enhancing technology which enhances color differences between a colon lesion and surrounding mucosa with enough brightness to illuminate the wide colorectal lumen. The aim of this study is to compare colorectal polyp detection using LCI with white light imaging (WLI).

    Methods This systematic review and meta-analysis were performed based on a registered protocol of the International Prospective Register of Systematic Review (PROSPERO, ID: CRD42019136918). Randomized controlled trials and prospective studies comparing LCI with WLI for colorectal polyp detection were selected. Outcomes included overall polyp/adenoma detection and additional polyp detection at a second observation. Outcomes were documented by pooled risk ratios (RR) with 95% confidence interval (CI) using the Mantel-Haenszel random effect model.

    Results Six studies were included. LCI showed significant superiority for polyp and adenoma detection compared with WLI (RR 1.15, 95%CI 1.04-1.29, p=0.010 for polyp detection, RR 1.29, 95%CI 1.14-1.47, p< 0.001 for adenoma detection). LCI had a greater likelihood of increasing the number of polyps detected per patient compared with WLI (mean difference 0.29, 95%CI -0.10-0.68, p=0.150). LCI significantly increased the number of adenomas detected per patient compared with WLI (mean difference 0.27, 95%CI 0.03-0.50, p=0.030). LCI had a trend toward an increased number of flat polyps detected per patient compared with WLI (mean difference 0.22, 95%CI -0.02-0.45, p=0.070). LCI had a significantly higher rate of additional polyp detection compared with WLI in the right colon (RR 2.68, 95%CI 1.71-4.19, p< 0.001).

    Conclusions LCI has significantly greater polyp and adenoma detection rates and detection rate of previously missed polyps compared with WLI. LCI has the potential to decrease the rate of interval cancers by improving colorectal polyp detection due to its brightness and color enhancement. We recommend the initial use of LCI for routine colonoscopy.


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