Endoscopy 2020; 52(S 01): S59
DOI: 10.1055/s-0040-1704184
ESGE Days 2020 oral presentations
Thursday, April 23, 2020 16:30 – 18:00 Removing doubt from the red-out: Liffey Meeting Room 1 Upper GI hemostasis
© Georg Thieme Verlag KG Stuttgart · New York

TIME TRENDS IN ACUTE UPPER GASTROINTESTINAL BLEEDING: IS SOMETHING CHANGED IN PAST 10 YEARS?

V Milivojevic
1   Clinical Center of Serbia, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
2   Belgrade University, School of Medicine, Belgrade, Serbia
,
I Rankovic
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
,
D Popovic
2   Belgrade University, School of Medicine, Belgrade, Serbia
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
,
T Glisic
2   Belgrade University, School of Medicine, Belgrade, Serbia
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
,
O Matejic
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
,
D Tomic
2   Belgrade University, School of Medicine, Belgrade, Serbia
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
,
B Milicic
4   School of Dental Medicine, Department of Medical Statistics and Informatics, Belgrade, Serbia
,
I Jovanovic
5   Clinical center of Serbia, Belgrade, Serbia
6   Belgrade University, Belgrade, Serbia
,
M Krstic
2   Belgrade University, School of Medicine, Belgrade, Serbia
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
,
T Milosavljevic
2   Belgrade University, School of Medicine, Belgrade, Serbia
3   Belgrade University, Clinic for Gastroenterology and Hepatology, Belgrade, Serbia
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

Also available at
 
 

    Aims To evaluate changes in clinico-epidemiologic characteristics of patients who presented with acute upper gastrointestal bleeding (AUGIB) during the last 10 years in Serbia

    Methods Data from 126 patients admitted with AUGIB in our center from January 1. to December 31., 2018. were compared with retrospectively collected data from 124 patients admitted with AUGIB in 2013. year and with 121 patients from 2008. year.

    Results Mean age of patients increased from 63.84±14.1 years to 65.71±14.27 and 68.92±12.77, and the number of patient´s comorbidity,too. The percentage of NSAID´s and antiplatelets use remained stable (63.63% vs. 68.55% vs. 65.87%), whereas the use of oral anticoagulants drugs increased significantly during this period (from 6.44%, across 12.1% in 2013. to 16.67%, P=0.041). In 2008. year 31.4% of AUGIB was from duodenal ulcer following gastric ulcer (26.44%), variceal bleeding (15.7%), gastric erosions (12.4%), duodenal erosions (8.26%), gastric and oesophageal cancers (7.44%) and other reasons in 5.79%. Main reason for AUGIB in 2013. year was also duodenal ulcer (25%), duodenal erosions are second with 19.35% whilst gastric ulcer (15.32%), gastric erosions (10.48%), gastric and oesophageal cancers (12.9%) and variceal bleeding (6.45%) are coming after. In the year 2018. most frequent reason for AUGIB were duodenal erosions with 24.6%, following duodenal ulcers 23.42%, gastric ulcers (15.87%), variceal bleeding (11.11%), gastric erosions (8.73%), gastric and oesophageal cancers (8.73%) and other reasons with 16.67%. During the period of these 10 years duodenal erosions increased significantly (X2=11.84, p=0.0027, p‹0.05) while gastric ulcer decreased significantly (X2=6.21, p=0.044, p‹0.05). Overall mortality was 14.05% in 2008., 9.68% in 2013. and 10.32% in the year 2018.

    Conclusions Patients with AUGIB are older with more comorbidities, their mortality remains unchanged. Main risk factors for AUGIB are NSAID´s use with clear trend of decreasing of peptic ulcer disease, mainly gastric ulcers like a reason of haemmoraige.


    #