UTILITY OF SPYBITE BIOPSIES THROUGH UNCOVERED SELF EXPANDABLE METAL STENT FOR DIAGNOSIS OF CHOLANGIOCARCINOMA

Tissue acquisition to confirm the diagnosis in patients with suspected cholangiocarcinoma poses significant challenges. In the last few years targeted biopsies obtained with the SpyBite biopsy forceps through Peroral Cholangioscopy has shown promising diagnostic yields in cases with negative brush cytology or fine needle aspiration; but yet remains very challenging in most difficult cases. We believe that the video attached for one of the four cases we did is the first to describe the utility of Peroral Cholangioscopy in obtaining targeted biopsies through mesh of uncovered self-expandable metallic-stent (UcSEMS) in patients with inoperable cholangiocarcinoma who already had UcSEMS in-situ.