Double-Balloon Enteroscopy-Facilitated Ischaemic Polypectomy Of Small-Bowel Polyps In Patients With Peutz-Jeghers Syndrome

Ischaemic-polypectomy with detachable-snares or endoclips at double-balloon enteroscopy (DBE) is emerging as a promising technique for the minimally-invasive management of small-bowel polyps in patients with Peutz-Jeghers syndrome (PJS).

In this case series, 46 polyps were treated during 9 therapeutic DBEs performed in 4 patients. Seven polyps >20mm in size required loop ligation with a detachable-snare. No immediate or late adverse events occurred. All patients remained asymptomatic during follow-up (mean 19; range 1-48 months). None required subsequent surgery.

Ischaemic-polypectomy facilitated by DBE appears to be a safe and effective endotherapeutic option for endotherapy of small-bowel polyps in patients with PJS.

Age/Gender	Number of procedures (antero/retro)	Total polyps	Clipping	Detachable snare for polyps >20mm
50/M	2 (1/1)	17	17	-
56/M	1 (1/-)	14	14	-
29/F	3 (1/2)	7	4	3
29/M	3 (3/-)	8	4	4

Citation Skamnelos A, Murino A, Lazaridis N et al. eP141V DOUBLE-BALLOON ENTEROSCOPY-FACILITATED ISCHAEMIC POLYPECTOMY OF SMALL-BOWEL POLYPS IN PATIENTS WITH PEUTZ-JEGHERS SYNDROME. Endoscopy 2021; 53: S143.

Publication History

Article published online:
19 March 2021