Oral Diet and Survival After the Placement of Enteric Stens in Advanced Gastric Neoplasms

Aims Antro-duodenal segment obstruction (ADSO) is a frequent complication in patients with locally advanced gastric neoplasms. The palliation of these obstructions can be performed with surgery or with the placement of metallic stents.

This study aims to assess the long-term clinical efficacy of enteric prostheses in palliating patients with ADSO for gastric neoplasms.

Methods Retrospective, multicenter cohort study, comprising 73 patients with gastric neoplasms who underwent stent placement for ADSO between January 2005 and December 2019. All patients included were followed up to death. The main outcomes assessed were (1) survival and (2) prosthesis patency (3) improvement in oral diet intake. Predictors of prosthesis survival and patency were evaluated using proportional Cox regressions and Kaplan Meier curves.

Results Enteric stens were placed in 37 women (50.7 %) and 36 men (49.3 %), with a median age of 80 years (min. 44; max. 94). The median survival was 100 days (p25 = 38 days; p75 = 264 days). 91.8 % (67/73) of the patients maintained an oral diet until death, without the need for surgery. 76.7 % (56/74) did not need other endoscopic interventions. 88 % of patients maintained a solid diet (GOOSS 2-3) until death. In Cox regression, the only factor associated with increased survival is chemotherapy (hazard ratio = 0.323; 95 % confidence interval = 0.159-0.659; p = 0.002).

Conclusions Enteric stents are an effective and safe minimally invasive technique for palliation of antro-duodenal segment obstruction caused by gastric neoplasms.

Most patients maintain an oral diet until death, without the need for additional interventions.

Citation: Moreira M, Leite M, Elisa A et al. eP155 ORAL DIET AND SURVIVAL AFTER THE PLACEMENT OF ENTERIC STENS IN ADVANCED GASTRIC NEOPLASMS. Endoscopy 2021; 53: S147.

Publication History

Article published online:
19 March 2021