CC-Clear (Colon Capsule Cleansing Assessment And Report): The Novel Scale to Evaluate the Quality of Bowel Preparation in Capsule Colonoscopy – a Prospective Validation Study

Aims: CC-CLEAR ( C olon C apsule CLE ansing A ssessment and R eport) is a novel quantitative bowel preparation scale for CC, recently developed by our department, that displays excellent interobserver and intraobserver agreement rates when compared to other current used scales.

Aim: Validation of CC-CLEAR.

Methods Consecutive CCs since 2015 until 2020. A cluster of 79 patients was followed prospectively since January 2019 (2 months minimum follow-up). Videos were reviewed by two experienced physicians, and post CC recommendations decided by a panel of experts. Age, gender, indication for CC, colonic transit time, findings, complications and recommendations (early CC repetition, CC in three years or need for early colonoscopy) were included, as well as data from colonoscopies performed following CC. CC-CLEAR (continuous and categorical) was assessed.

Results 128 patients, 90 (70.3 %) females, with a mean age of 65 years old. Endoscopic findings were reported in 95 (74,2 %) CCs, 48 (50.5 %) of which were polyps. Twenty-five (19.5 %) colonoscopies were recommended after CC, including 18 (72 %) polypectomies and 5 (20 %) other endoscopic treatments. CC-CLEAR influenced the detection of CC findings (OR 1,26 95 % IC [1,02-1,57] p-value 0,035) after adjusting for other covariables. CC-CLEAR affected the polyp detection rate (OR 1,26 95 % IC [1,01-1,56] p-value 0,031), the need for colonoscopy treatment (OR 1.41 95 % IC [1.02-1.94] p-value 0,03), the decision for early CC repetition (OR 0,27 95 % IC [0.14-0.49] p-value < 0,001), the suggestion for CC in three years’ time (OR 1.43 95 % IC [1.01-2.02] p-value < 0,041) and presented a statistical trend for early colonoscopy recommendation (OR 1.20 95 % IC [0.93-1.54] p-value 0,15).

Conclusions: CC-CLEAR is a new, reliable cleansing scale that impacts CC findings detection rate, the need for therapeutic colonoscopy and the recommendations regarding the timing of following colonoscopy.

Citation: de Sousa Magalhães R, Sousa-Pinto B, Boal Carvalho P etal. eP290 CC-CLEAR (COLON CAPSULE CLEANSING ASSESSMENT AND REPORT): THE NOVEL SCALE TO EVALUATE THE QUALITY OF BOWEL PREPARATION IN CAPSULE COLONOSCOPY – A PROSPECTIVE VALIDATION STUDY. Endoscopy 2021; 53: S193.

Publication History

Article published online:
19 March 2021