Efficacy And Safety Of Full Thickness Resection (FTR) For Colonic Lesions In A Tertiary Care Center

Aims Aim of this study is to determine the effectiveness and safety of FTR of colic lesions not amenable to resection with traditional techniques or for treating lesions bigger than 2 cm or with a combined endoscopic treatment (EMR and FTR) or with multiple FTR.

Methods We describe our experience, in a tertiary care center, using the FTRD for advanced polyps or scarred lesions. In this study we analyzed demographic, endoscopic, histological data, rate of success and complication.

Results Between April 2017 and June 2020, 23 patients (15 males) underwent a colonoscopy with FTR. The mean age was 69 years. In this series of patient, 12 had recurrent adenomas, 7 had high-grade displasia or intramucosal carcinoma and 4 had a non lifting lesion. Resection was technically successful in all patients. One patient underwent three consecutive procedures in order to obtain a complete resection of the lesion. One patient underwent a combined resection with EMR and FTR for the non lifting part of the polyp. Histologically complete resection (R0) was achieved in 21/23 (91 %). There were two major complications (perforation), with a total rate of complication of 8 % (2/23 patients). In 3/23 (13 %) we found a residual lesion at the follow up colonoscopy, performed between 4 and 6 months. Two of these patients were treated endoscopically, one as a completion of multiple consecutive FTR and one with traditional EMR of the residual adenoma. The third patient decided not to intervene.

Conclusions In our experience, FTR is a safe and useful technique for treating colonic lesions not amenable to resection with traditional technique or in patient with a high risk for surgery. It could be useful, in multiple consecutive procedures, for treating lesion bigger than 2 cm or in combined procedures in order to complete the resection in non lifting part of lesion.

Citation Magarotto A, Cavalcoli F, Mancini A et al. eP470 EFFICACY AND SAFETY OF FULL THICKNESS RESECTION (FTR) FOR COLONIC LESIONS IN A TERTIARY CARE CENTER. Endoscopy 2021; 53: S252.

Publication History

Article published online:
19 March 2021