Sex- and Age-Dependent Changes in Polysensitization to Common Aeroallergens over 20 Years

Introduction The prevalence of airway allergies in Europe has increased from 23 % to 31 % in recent years. Polysensitization is associated with the development and severity of relevant allergies, particularly allergic asthma.

Objective Age- and sex-dependent mono- and polysensitization profiles were analyzed, as well as patterns of sensitization using skin prick test (SPT) reactivity to the most common aeroallergens in Germany.

Patients and Methods From 1998 to 2017, SPTs were retrospectively analyzed in 2,886 symptomatic patients, referred to the University Medical Center Göttingen, located in central Germany. The major aeroallergen groups early flowering tree pollen, grass pollen, and house dust mites were evaluated in this study.

Results Polysensitization to the most common aeroallergen groups increased significantly over 20 years. Boys and young men displayed the most remarkable rise in total sensitization rates in our study group over time.

Discussion Our patient-based study demonstrates a continuing increase in polysensitization rates over the last 20 years, with boys and young men being most frequently affected. Our data–without being a population-based study–suggest a scenario with climbing rates of allergic rhinitis and asthma.

Poster-PDF A-1415.pdf

Conflict of interest

Der Erstautor gibt keinen Interessenskonflikt an.

Publication History

Article published online:
13 May 2021