Solitary fibrous tumor in the upper eyelid - a rare case

Introduction: Solitary fibrous tumors (SFT) are rare spindle-cell tumors that mostly occur in the pleura. In the ENT area, SFTs are extremely rare and have been described in the nasal cavity, thyroid gland, parotid gland and orbit. The tumors are slowly growing and T2-weighted MRI typically reveals an iso- to hypointense mass. In immunohistochemistry, SFTs can be stained with CD34 and have a nuclear positivity for STAT6. SFTs are mostly benign tumors but in rare cases, they also can be malignant. SFTs are treated by a complete surgical excision.

Case: A 70-year-old female patient came to our outpatient clinic with a slowly growing and painless size-progressive tumor in the right upper eyelid. Her vision was not affected and diplopia was not present. 12 months ago, an unspecified tumor from the right upper eyelid was removed alio loco. MRI demonstrated a well-defined tumor with enhancement in the T1 and T2 weighing in the area of the right upper eyelid. Subsequently, the mass was removed through an upper blepharoplasty approach.

Results: Immunhistochemistry demonstrated nuclear positivity for STAT6 and positivity for CD99 and CD34.

Conclusions Solitary fibrous tumors are a rare in the ENT area. The nuclear positivity for STAT6 in immunohistochemistry is considered to be proof of the tumor entity. Since the tumor can occur as a malignant tumor disease in rare cases, a complete excision as well as a regular clinical tumor follow-up is mandatory.

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Conflict of interest

Der Erstautor gibt keinen Interessenskonflikt an.

Publication History

Article published online:
13 May 2021