J Neurol Surg B Skull Base 2022; 83(S 01): S1-S270
DOI: 10.1055/s-0042-1744012
Presentation Abstracts
Poster Presentations

Prevalence and Efficacy of Corticosteroid Use for Sudden Sensorineural Hearing Loss in Vestibular Schwannoma: A Survey Study of the Acoustic Neuroma Association

Jeffrey D. Bernstein
1   UC San Diego Health, San Diego, California, United States
,
Omid Moshtaghi
1   UC San Diego Health, San Diego, California, United States
,
Eric Y. Du
2   UC San Diego School of Medicine, San Diego, California, United States
,
Shane Shahrestani
3   USC School of Medicine
,
Yin Ren
4   Ohio State University College of Medicine, Columbus, Ohio, United States
,
Kareem O. Tawfik
5   Vanderbilt University Medical Center, Nashville, Tennessee, United States
,
Marc S. Schwartz
1   UC San Diego Health, San Diego, California, United States
,
Rick A. Friedman
1   UC San Diego Health, San Diego, California, United States
› Author Affiliations
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    Objective: To investigate the incidence of sudden sensorineural hearing loss (SSNHL) in patients with vestibular schwannoma (VS) and the efficacy of corticosteroid-based treatment.

    Study Design: Cross-sectional online survey.

    Setting: Online survey.

    Patients: Patient members of the Acoustic Neuroma Association (ANA), residing in the United States, with self-reported history of sporadic, radiographically confirmed VS.

    Interventions: A comprehensive survey was distributed online between February 2020 and June 2021 via the ANA. Data collection was self-reported and included demographics, past medical history, VS-related symptoms, SSNHL, treatment modalities, and surgical and quality of life outcomes.

    Main Outcome Measures: Self-reported hearing recovery for VS-related SSNHL.

    Results: In total, 232 responses were collected in the study period, with responses from residents of 46 states. Of this cohort, 222 patients noted symptoms as a direct result of VS: most commonly hearing loss (n = 131), tinnitus (n = 77), and balance difficulties / dizziness (n = 72). One-hundred patients (43.1%) reported SSNHL onset prior to receiving treatment. Compared with those that did not experience SSNHL, this cohort had greater rates of hearing loss (68.0% vs 50.4%, p = 0.002), facial numbness (12.0% vs. 3.2%, p = 0.012), and fatigue (13.0% vs. 4.8%, p = 0.032). The majority of sampled patients underwent surgical resection (59.4%, n = 138). Hearing recovery in patients with SSHNL was similar between groups who reported or did not report corticosteroid treatment (18.2% vs. 17.6%, p = 0.947).

    Conclusion: The incidence of SSNHL in VS may be greater than previously reported. Corticosteroid treatment may not be an effective intervention for hearing recovery in those with VS-related SSNHL.


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    No conflict of interest has been declared by the author(s).

    Publication History

    Article published online:
    15 February 2022

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