Diagnosis of intrabiliary metastasis of colorectal cancer by cholangioscopy

Abstract Text Two cases of intrabiliary metastasis of colorectal cancer (CRC) diagnosed with endoscopic retrograde cholangiopancreatography (ERCP) and cholangioscopy using the SpyGlass DSII system. In case 1, ERCP showed a long asymmetric stricture of the common bile duct and dilatation of intrahepatic ducts. Cholangioscopy visualized a mass arising from the choledochal wall, with villous pattern and irregular vessels. In case 2, the cholangiography showed stenosis of the common hepatic duct and retrograde dilatation. Cholangioscopy visualized a non transversable stenosis, with erythematous mucosa and neovessels. Biopsies confirmed metastases of colorectal adenocarcinoma in both cases. Intraductal biliary growthis an exceptional localization of CRC metastases and differentiating it from cholangiocarcinoma is a diagnostic challenge in which cholangioscopy is a very valuable tool. [1] [2] [3]

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Conflicts of interest

Authors do not have any conflict of interest to disclose.

• References

• 1 Dong Y, Patel H, Patel C.. Intrabiliary hepatic metastasis of colorectal carcinoma mimick ing primary cholangiocarcinoma: a case report and review of the literature. Case Rep Pathol 2016; 2016: 4704781
• 2 Estrella JS, Othman ML, Taggart MW. et al. Intrabiliary growth of liver metastases: clinicopathologic features, prevalence, and outcome. Am J Surg Pathol 2013; 37 (10) 1571-1579
• 3 Okamoto T.. Malignant biliary obstruction due to metastatic non-hepato-pancreato-biliary cancer. World J Gastroenterol 2022; 28 (10) 985-1008 PMID: 35431494; PMCID: PMC8968522

Publication History

Article published online:
15 April 2024