The clinical evaluation of platelet-rich plasma on free gingival graft's donor site wound healing

Mahmoud Khosravi Samani; Bardia Vadiati Saberi; S. M. Ali Tabatabaei; Mahdjoube Goldani Moghadam

doi:10.4103/ejd.ejd_76_17

European Journal of Dentistry, Table of Contents

CC BY-NC-ND 4.0 · Eur J Dent 2017; 11(04): 447-454
DOI: 10.4103/ejd.ejd_76_17

Original Article

Dental Investigation Society

The clinical evaluation of platelet-rich plasma on free gingival graft's donor site wound healing

Authors

Mahmoud Khosravi Samani

¹Department of Periodontology, Oral Health Research Center, Faculty of Dentistry, Babol University of Medical Sciences, Babol, Iran
Bardia Vadiati Saberi

²Department of Periodontology, Faculty of Dentistry, Guilan University of Medical Sciences, Guilan, Iran
S. M. Ali Tabatabaei

³Department of Periodontology, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran
Mahdjoube Goldani Moghadam

⁴Department of Orthodontics, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran

Abstract

ABSTRACT

Objective: It has been proved that platelet-rich plasma (PRP) can promote wound healing. In this way, PRP can be advantageous in periodontal plastic surgeries, free gingival graft (FGG) being one such surgery. Materials and Methods: In this randomized split-mouth controlled trial, 10 patients who needed bilateral FGG were selected, and two donor sites were randomly assigned to experience either natural healing or healing-assisted with PRP. The outcome was assessed based on the comparison of the extent of wound closure, Manchester scale, Landry healing scale, visual analog scale, and tissue thickness between the study groups at different time intervals. Statistical Analysis Used: Repeated measurements of analysis of variance and paired t-test were used. Statistical significance was P ≤ 0.05. Results: Significant differences between the study groups and also across different time intervals were seen in all parameters except for the changes in tissue thickness. Conclusion: PRP accelerates the healing process of wounds and reduces the healing time.

Key words:

Free gingival graft - platelet-rich plasma - wound healing

Full Text

References

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