Download PDF
Dialyse aktuell 2018; 22(08): 360-367
DOI: 10.1055/a-0742-4037
Schwerpunkt | Dialyse
© Georg Thieme Verlag KG Stuttgart · New York

Verträglichkeit bei Heimdialyseverfahren

Was ist neben medizinischen Aspekten zu beachten?
Claudia Karger
1   KfH-Nierenzentrum und Abteilung Nephrologie, Klinikum Sankt Georg, Leipzig
,
Joachim Beige
1   KfH-Nierenzentrum und Abteilung Nephrologie, Klinikum Sankt Georg, Leipzig
2   Martin-Luther-Universität Halle/Wittenberg
,
Benno Kitsche
3   KfH-Nierenzentrum Köln-Merheim, Beauftragter des KfH-Vorstands zur Förderung und Entwicklung der Heimdialyseverfahren in Deutschland, Neu-Isenburg
› Author Affiliations
Further Information

Publication History

Publication Date:
29 October 2018 (online)

Also available at
    Permissions and Reprints

Zusammenfassung

Stärker als die zentrumsbasierten Verfahren bieten Heimverfahren die Möglichkeit, die sozialen und die mit Lebensqualität assoziierten Unverträglichkeiten der Nierenersatztherapie zu adressieren. Im vorliegenden Artikel werden die Aspekte einer nicht nur medizinischen Verträglichkeit beschrieben und zu den Möglichkeiten, die Heimverfahren bieten, in Beziehung gesetzt. Dennoch können auch schwerpunktmäßig medizinische Probleme wie hämodynamische Instabilität, Blutdruck- und Volumenregulation mittels der flexibleren Möglichkeiten der Heimdialyseverfahren erfolgreich angegangen werden. Der Artikel zeigt geeignete Herangehensweisen und stellt vor allem das Verständnis und die Lösungsansätze durch betroffene Patienten selbst in den Mittelpunkt der Überlegungen. Dieses „Shared Decision Making“ und die unter anderem darauf basierenden Bewältigungsstrategien stellen einen sowohl neuartigen als auch notwendigen Ansatz bei der Versorgung unserer lebenslang erkrankten Patienten dar.

 

  • Literatur

  • 1 Foley RN, Parfrey PS. Cardiovascular disease and mortality in ESRD. J Nephrol 1998; 11: 239-245
    PubMedSearch in Google Scholar
  • 2 Haag-Weber M, Kribben A. Peritonealdialyse. Der Nephrologe 2017; 12: 4-5 doi:10.1007/s11560–016–0130-x
    CrossrefSearch in Google Scholar
  • 3 Mendelssohn DC, Mujais SK, Soroka SD. et al. A prospective evaluation of renal replacement therapy modality eligibility. Nephrol Dial Transplant 2009; 24: 555-561 doi:10.1093/ndt/gfn484
    PubMedSearch in Google Scholar
  • 4 Devoe DJ, Wong B, James MT. et al. Patient education and peritoneal dialysis modality selection: a systematic review and meta-analysis. Am J Kidney Dis 2016; 68: 422-433 doi:10.1053/j.ajkd.2016.02.053
    CrossrefPubMedSearch in Google Scholar
  • 5 Van Biesen W, van der Veer SN, Murphey M. et al. Patients’ perceptions of information and education for renal replacement therapy: an independent survey by the European Kidney Patients’ Federation on information and support on renal replacement therapy. PLoS One 2014; 9: e103914 doi:10.1371/journal.pone.0103914
    CrossrefPubMedSearch in Google Scholar
  • 6 Robinski M, Neumann D, Mau W. et al. The Choice of Renal Replacement Therapy (CORETH) Project: Der psychosoziale Status in der Frühphase der Peritoneal- und Hämodialyse. Nieren- und Hochdruckkrankheiten 2016; 45: 194-201 doi:10.5414/NHX01777
    Search in Google Scholar
  • 7 MNC GmbH. Jahresbericht für den G-BA für das Berichtsjahr. 2017 Im Internet: www.g-ba.de/downloads/17–98–4613/2018–07–19_QSD-RL_MNC-Jahresbericht-2017_Bericht.pdf Stand: 26.09.2018
    PubMedSearch in Google Scholar
  • 8 Kitsche B. Assistierte Heimdialyse: Anwendung bei älteren Dialysepatienten. Dial aktuell 2018; 22: 165-169 doi:10.1055/a-0597–6259
    Search in Google Scholar
  • 9 Fenton SS, Schaubel DE, Desmeules M. et al. Hemodialysis versus peritoneal dialysis: a comparison of adjusted mortality rates. Am J Kidney Dis 1997; 30: 334-342
    CrossrefPubMedSearch in Google Scholar
  • 10 Jahn M, Bienholz A, Kribben A. Neue Indikationen für die Peritonealdialyse. Der Nephrologe 2017; 12: 6-13 doi:10.1007/s11560–016–0121-y
    CrossrefSearch in Google Scholar
  • 11 Flythe JE, Hilliard T, Castillo G. et al. Symptom prioritization among adults receiving in-center hemodialysis: a Mixed Methods Study. Clin J Am Soc Nephrol 2018; 13: 735-745 doi:10.2215/CJN.10850917
    CrossrefPubMedSearch in Google Scholar
  • 12 Daugirdas JT. Simplified equations for monitoring Kt/V, PCRn, eKt/V, and ePCRn. Adv Ren Replace Ther 1995; 2: 295-304
    CrossrefPubMedSearch in Google Scholar
  • 13 Schwenger V, Remppis BA, Westenfeld R. et al. Dialyse- und Ultrafiltrationsverfahren bei kardiorenalem Syndrom: Empfehlung der Arbeitsgemeinschaft „Herz – Niere“ der Deutschen Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. und der Deutschen Gesellschaft für Nephrologie e. V. Kardiologe 2014; 8: 26-35 doi:10.1007/s12181–013–0549–5
    CrossrefSearch in Google Scholar
  • 14 Kitsche B. Heimdialyse: mehr Eigenverantwortung, aber auch mehr Flexibilität. Spektrum Dial Apher 2016; 6: 6-7
    Search in Google Scholar
  • 15 Boudville NC, Cordy P, Millman K. et al. Blood pressure, volume, and sodium control in an automated peritoneal dialysis population. Perit Dial Int 2007; 27: 537-543
    PubMedSearch in Google Scholar
  • 16 Liao C-T, Chen Y-M, Shiao C-C. et al. Rate of decline of residual renal function is associated with all-cause mortality and technique failure in patients on long-term peritoneal dialysis. Nephrol Dial Transplant 2009; 24: 2909-2914 doi:10.1093/ndt/gfp056.
    CrossrefPubMedSearch in Google Scholar
  • 17 Fleming SJ, Powell J, Baker LR. et al. Influence of intraperitoneal dialyzate on blood pressure during continuous ambulatory peritoneal dialysis. Clin Nephrol 1983; 19: 132-133
    PubMedSearch in Google Scholar
  • 18 Verbeke F, Van Biesen W, Pletinck A. et al. Acute central hemodynamic effects of a volume exchange in peritoneal dialysis. Perit Dial Int 2008; 28: 142-148
    PubMedSearch in Google Scholar
  • 19 Pletinck A, Verbeke F, Van Bortel L. et al. Acute central haemodynamic effects induced by intraperitoneal glucose instillation. Nephrol Dial Transplant 2008; 23: 4029-4035 doi:10.1093/ndt/gfn384
    CrossrefPubMedSearch in Google Scholar
  • 20 Wang X, Axelsson J, Lindholm B. et al. Volume status and blood pressure in continuous ambulatory peritoneal dialysis patients. Blood Purif 2005; 23: 373-378 doi:10.1159/000087194
    CrossrefPubMedSearch in Google Scholar
  • 21 Orihuela O, de Jesús Ventura M, Ávila-Díaz M. et al. Effect of icodextrin on heart rate variability in diabetic patients on peritoneal dialysis. Perit Dial Int 2014; 34: 57-63 doi:10.3747/pdi.2012.00279
    CrossrefPubMedSearch in Google Scholar
  • 22 Murashima M, Kumar D, Doyle AM. et al. Comparison of intradialytic blood pressure variability between conventional thrice-weekly hemodialysis and short daily hemodialysis. Hemodial Int 2010; 14: 270-277 doi:10.1111/j.1542–4758.2010.00438.x
    CrossrefPubMedSearch in Google Scholar
  • 23 Okada K, Abe M, Hagi C. et al. Prolonged protective effect of short daily hemodialysis against dialysis-induced hypotension. Kidney Blood Press Res 2005; 28: 68-76 doi:10.1159/000083586
    CrossrefPubMedSearch in Google Scholar
  • 24 Murphy SW, Foley RN, Barrett BJ. et al. Comparative mortality of hemodialysis and peritoneal dialysis in Canada. Kidney Int 2000; 57: 1720-1726 doi:10.1046/j.1523–1755.2000.00017.x
    CrossrefPubMedSearch in Google Scholar
  • 25 Yeates K, Zhu N, Vonesh E. et al. Hemodialysis and peritoneal dialysis are associated with similar outcomes for end-stage renal disease treatment in Canada. Nephrol Dial Transplant 2012; 27: 3568-3575 doi:10.1093/ndt/gfr674
    CrossrefPubMedSearch in Google Scholar
  • 26 Lukowsky LR, Mehrotra R, Kheifets L. et al. Comparing mortality of peritoneal and hemodialysis patients in the first 2 years of dialysis therapy: a marginal structural model analysis. Clin J Am Soc Nephrol 2013; 8: 619-628 doi:10.2215/CJN.04810512
    CrossrefPubMedSearch in Google Scholar
  • 27 Vonesh EF, Snyder JJ, Foley RN. et al. The differential impact of risk factors on mortality in hemodialysis and peritoneal dialysis. Kidney Int 2004; 66: 2389-2401 doi:10.1111/j.1523–1755.2004.66028.x
    CrossrefPubMedSearch in Google Scholar
  • 28 Korevaar JC, Jansen MA, Merkus MP. et al. Quality of life in predialysis end-stage renal disease patients at the initiation of dialysis therapy. The NECOSAD Study Group. Perit Dial Int 2000; 20: 69-75
    PubMedSearch in Google Scholar
  • 29 Woods JD, Port FK, Stannard D. et al. Comparison of mortality with home hemodialysis and center hemodialysis: a national study. Kidney Int 1996; 49: 1464-1470
    CrossrefPubMedSearch in Google Scholar
  • 30 Mathew A, McLeggon JA, Mehta N. et al. Mortality and hospitalizations in intensive dialysis: a systematic review and meta-analysis. Can J Kidney Health Dis 2018; 5: 2054358117749531 doi:10.1177/2054358117749531
    Search in Google Scholar
  • 31 Collins AJ, Foley RN, Herzog C. et al. US Renal Data System 2012 Annual Data Report. Am J Kidney Dis 2013; 61 (01) (Suppl. 01) A7-e1–476 doi:10.1053/j.ajkd.2012.11.031
    CrossrefPubMedSearch in Google Scholar
  • 32 Eknoyan G, Beck GJ, Cheung AK. et al. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 2002; 347: 2010-2019 doi:10.1056/NEJMoa021583
    CrossrefPubMedSearch in Google Scholar
  • 33 Hall YN, Larive B, Painter P. et al. Effects of six versus three times per week hemodialysis on physical performance, health, and functioning: Frequent Hemodialysis Network (FHN) randomized trials. Clin J Am Soc Nephrol 2012; 7: 782-794 doi:10.2215/CJN.10601011
    CrossrefPubMedSearch in Google Scholar
  • 34 Chertow GM, Levin NW, Beck GJ. et al. In-center hemodialysis six times per week versus three times per week. N Engl J Med 2010; 363: 2287-2300 doi:10.1056/NEJMoa1001593
    CrossrefPubMedSearch in Google Scholar
  • 35 Walsh M, Manns BJ, Klarenbach S. et al. The effects of nocturnal compared with conventional hemodialysis on mineral metabolism: A randomized-controlled trial. Hemodial Int 2010; 14: 174-181 doi: 10.1111/j.1542–4758.2009.00418.x
    CrossrefPubMedSearch in Google Scholar
  • 36 Ok E, Duman S, Asci G. et al. Comparison of 4- and 8-h dialysis sessions in thrice-weekly in-centre haemodialysis: a prospective, case-controlled study. Nephrol Dial Transplant 2011; 26: 1287-1296 doi:10.1093/ndt/gfq724
    CrossrefPubMedSearch in Google Scholar
  • 37 Charra B. Improving adequacy improves haemodialysis outcome. EDTNA ERCA J 2000; 26: 6-10
    PubMedSearch in Google Scholar
  • 38 Rocco MV, Lockridge RSJ, Beck GJ. et al. The effects of frequent nocturnal home hemodialysis: the frequent hemodialysis network nocturnal trial. Kidney Int 2011; 80: 1080-1091 doi:10.1038/ki.2011.213
    CrossrefPubMedSearch in Google Scholar
  • 39 Lowrie EG, Huang WH, Lew NL. Death risk predictors among peritoneal dialysis and hemodialysis patients: a preliminary comparison. Am J Kidney Dis 1995; 26: 220-228
    CrossrefPubMedSearch in Google Scholar
  • 40 Diaz-Buxo JA, Lowrie EG, Lew NL. et al. Quality-of-life evaluation using Short Form 36: comparison in hemodialysis and peritoneal dialysis patients. Am J Kidney Dis 2000; 35: 293-300
    CrossrefPubMedSearch in Google Scholar
  • 41 Wasserfallen JB, Halabi G, Saudan P. et al. Quality of life on chronic dialysis: comparison between haemodialysis and peritoneal dialysis. Nephrol Dial Transplant 2004; 19: 1594-1599 doi:10.1093/ndt/gfh175
    CrossrefPubMedSearch in Google Scholar
  • 42 Kang SH, Do JY, Lee SY. et al. Effect of dialysis modality on frailty phenotype, disability, and health-related quality of life in maintenance dialysis patients. PLoS One 2017; 12: e0176814 doi:10.1371/journal.pone.0176814
    CrossrefPubMedSearch in Google Scholar
  • 43 Boateng EA, East L. The impact of dialysis modality on quality of life: a systematic review. J Ren Care 2011; 37: 190-200 doi:10.1111/j.1755–6686.2011.00244.x
    CrossrefPubMedSearch in Google Scholar
  • 44 Kalantar-Zadeh K, Kuwae N, Regidor DL. et al. Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int 2006; 70: 771-780 doi:10.1038/sj.ki.5001514
    CrossrefPubMedSearch in Google Scholar
  • 45 Murtagh FE, Addington-Hall J, Higginson IJ. The prevalence of symptoms in end-stage renal disease: a systematic review. Adv Chronic Kidney Dis 2007; 14: 82-99 doi:10.1053/j.ackd.2006.10.001
    CrossrefPubMedSearch in Google Scholar
  • 46 Iliescu EA, Coo H, McMurray MH. et al. Quality of sleep and health-related quality of life in haemodialysis patients. Nephrol Dial Transplant 2003; 18: 126-132
    CrossrefPubMedSearch in Google Scholar
  • 47 Unruh ML, Larive B, Eggers PW. et al. The effect of frequent hemodialysis on self-reported sleep quality: Frequent Hemodialysis Network Trials. Nephrol Dial Transplant 2016; 31: 984-991 doi:10.1093/ndt/gfw062
    CrossrefPubMedSearch in Google Scholar
  • 48 Hanly PJ, Gabor JY, Chan C. Daytime sleepiness in patients with CRF: impact of nocturnal hemodialysis. Am J Kidney Dis 2003; 41: 403-410 doi:10.1053/ajkd.2003.50066
    CrossrefPubMedSearch in Google Scholar
  • 49 Jaber BL, Schiller B, Burkart JM. et al. Impact of short daily hemodialysis on restless legs symptoms and sleep disturbances. Clin J Am Soc Nephrol 2011; 6: 1049-1056 doi:10.2215/CJN.10451110
    CrossrefPubMedSearch in Google Scholar
  • 50 Gigli GL, Adorati M, Dolso P. et al. Restless legs syndrome in end-stage renal disease. Sleep Med 2004; 5: 309-315 doi:10.1016/j.sleep.2004.01.014
    CrossrefPubMedSearch in Google Scholar
  • 51 Kawauchi A, Inoue Y, Hashimoto T. et al. Restless legs syndrome in hemodialysis patients: health-related quality of life and laboratory data analysis. Clin Nephrol 2006; 66: 440-446
    CrossrefPubMedSearch in Google Scholar
  • 52 Hiroshige K, Kabashima N, Takasugi M. et al. Optimal dialysis improves uremic pruritus. Am J Kidney Dis 1995; 25: 413-419
    CrossrefPubMedSearch in Google Scholar
  • 53 Ko MJ, Wu HY, Chen HY. et al. Uremic pruritus, dialysis adequacy, and metabolic profiles in hemodialysis patients: a prospective 5-year cohort study. PLoS One 2013; 8: e71404 doi:10.1371/journal.pone.0071404
    CrossrefPubMedSearch in Google Scholar
  • 54 Balaskas E, Szepietowski JC, Bessis D. et al. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol 2011; 6: 748-752 doi:10.2215/CJN.05490610
    CrossrefPubMedSearch in Google Scholar
  • 55 Rayner H, Baharani J, Smith S. et al. Uraemic pruritus: relief of itching by gabapentin and pregabalin. Nephron Clin Pract 2012; 122: 75-79 doi:10.1159/000349943
    CrossrefPubMedSearch in Google Scholar
  • 56 Solak Y, Biyik Z, Atalay H. et al. Pregabalin versus gabapentin in the treatment of neuropathic pruritus in maintenance haemodialysis patients: a prospective, crossover study. Nephrology 2012; 17: 710-717 doi:10.1111/j.1440–1797.2012.01655.x
    CrossrefPubMedSearch in Google Scholar
  • 57 Farrokhi F, Abedi N, Beyene J. et al. Association between depression and mortality in patients receiving long-term dialysis: a systematic review and meta-analysis. Am J Kidney Dis 2014; 63: 623-635 doi:10.1053/j.ajkd.2013.08.024
    CrossrefPubMedSearch in Google Scholar
  • 58 Niihata K, Fukuma S, Akizawa T. et al. Association of coping strategies with mortality and health-related quality of life in hemodialysis patients: The Japan Dialysis Outcomes and Practice Patterns Study. PLoS One 2017; 12: e0180498 doi:10.1371/journal.pone.0180498
    CrossrefPubMedSearch in Google Scholar
  • 59 Cukor D, Ver Halen N, Asher DR. et al. Psychosocial intervention improves depression, quality of life, and fluid adherence in hemodialysis. J Am Soc Nephrol 2014; 25: 196-206 doi:10.1681/ASN.2012111134
    CrossrefPubMedSearch in Google Scholar
  • 60 Anding K, Bär T, Trojniak-Hennig J. et al. A structured exercise programme during haemodialysis for patients with chronic kidney disease: clinical benefit and long-term adherence. BMJ Open 2015; 5: e008709 doi:10.1136/bmjopen-2015–008709
    CrossrefPubMedSearch in Google Scholar