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Synfacts 2009(4): 0438-0438  
DOI: 10.1055/s-0028-1087831
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Stereo- and Regioselective Synthesis of Amino Alcohols via Lithiation/Borylation of Aziridines

Contributor(s): Paul Knochel, Tobias Thaler
F. Schmidt, F. Keller, E. Vedrenne, V. K. Aggarwal*
University of Bristol, UK
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Publikationsverlauf

Publikationsdatum:
23. März 2009 (online)

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Significance

N-Protected aziridines were shown to be useful intermediates for highly enantio- and diastereoselective syntheses of β-amino alcohols as well as of amino alcohols bearing a quaternary stereogenic center.