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Synfacts 2009(4): 0410-0410  
DOI: 10.1055/s-0028-1087899
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Reagent Control in Asymmetric Allylboration of Chiral Aldehydes

Contributor(s): Mark Lautens, Jane Panteleev
B. Soto-Cairoli, J. A. Soderquist*
University of Puerto Rico, Rio Piedras, Puerto Rico
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Publication History

Publication Date:
23 March 2009 (online)

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Significance

The authors report an allylboration of α-amino aldehydes 2, which is under strict reagent control. This work presents a synthetic application of chiral borabicyclodecane (1) reported previously by the same group (J. Am. Chem. Soc. 2005, 127, 8044). Moderate yields and excellent enantioselectivities are obtained.