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Synthesis 2011(14): 2281-2290
DOI: 10.1055/s-0030-1260071
DOI: 10.1055/s-0030-1260071
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
E/Z-Selective Synthesis of Alkylidene-3-oxo-3H-isobenzofurans by Reaction of Silyl Enol Ethers with Phthaloyl Dichloride
Weitere Informationen
Received
22 March 2011
Publikationsdatum:
15. Juni 2011 (online)
Publikationsverlauf
Publikationsdatum:
15. Juni 2011 (online)
![](https://www.thieme-connect.de/media/synthesis/201114/lookinside/thumbnails/10.1055-s-0030-1260071-1.jpg)
Abstract
The reaction of silyl enol ethers with phthaloyl dichloride afforded alkylidene-3-oxo-3H-isobenzofurans with very good E/Z-selectivity.
Key Words
cyclizations - O-heterocycles - phthalic acid derivatives - silyl enol ethers
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For the AlCl3-catalyzed transformation of 1 into A, see ref. 12e.
16CCDC-821844 (5i), CCDC-823020 (5f), CCDC-823021 (6a), and CCDC-824363 (7a) contain all crystallographic details of this publication and are available free of charge at www.ccdc.cam.ac.uk/conts/retrieving.html or can be ordered from the following address: Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; Fax: +44(1223)336033; E-mail: deposit@ccdc.cam.ac.uk.