Eur J Pediatr Surg 2013; 23(04): 327-329
DOI: 10.1055/s-0032-1315810
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Georg Thieme Verlag KG Stuttgart · New York

Fracture Healing of an Osteodysplastic Femur in a Microcephalic Osteodysplastic Primordial Dwarfism II (MOPD II) Patient: A Case Report

Lisanne Sara Rigter
1   Department of Traumatology, University Medical Center Groningen, Groningen, The Netherlands
,
Mostafa El Moumni
1   Department of Traumatology, University Medical Center Groningen, Groningen, The Netherlands
,
Henk Jan ten Duis
1   Department of Traumatology, University Medical Center Groningen, Groningen, The Netherlands
,
Klaus Wilhelm Wendt
1   Department of Traumatology, University Medical Center Groningen, Groningen, The Netherlands
› Author Affiliations
Further Information

Publication History

08 January 2012

21 April 2012

Publication Date:
07 July 2012 (online)

Introduction

Femoral fractures are common in children. Choice of management is influenced by many factors, including age and size of the child, fracture pattern, associated injuries, and surgical and family motivations.[1] Microcephalic osteodysplastic primordial “dwarfism” type II (MOPD II) is a rare autosomal recessive condition with clinical signs of severe intrauterine and postnatal growth retardation, a progressive bony dysplasia with metaphyseal changes in the limbs and epiphyseal delay.[2] Femoral fractures in MOPD II patients have never been described. The purpose of this case report was to inform about fracture healing in this patient with dysplastic changes in the limbs.

 
  • References

  • 1 Anglen JO, Choi L. Treatment options in pediatric femoral shaft fractures. J Orthop Trauma 2005; 19 (10) 724-733
  • 2 Hall JG, Flora C, Scott Jr CI, Pauli RM, Tanaka KI. Majewski osteodysplastic primordial dwarfism type II (MOPD II): natural history and clinical findings. Am J Med Genet A 2004; 130A (1) 55-72
  • 3 Willems M, Geneviève D, Borck G , et al. Molecular analysis of pericentrin gene (PCNT) in a series of 24 Seckel/microcephalic osteodysplastic primordial dwarfism type II (MOPD II) families. J Med Genet 2010; 47 (12) 797-802
  • 4 Raney EM, Freccero DM, Dolan LA, Lighter DE, Fillman RR, Chambers HG. Evidence-based analysis of removal of orthopaedic implants in the pediatric population. J Pediatr Orthop 2008; 28 (7) 701-704