Synthesis of Alkoxymethyl Groups Containing Isoxazoles and Chromones

Abstract

An oxocarbenium ion mediated cyclization of (Z)-1,3-diarylprop-2-yn-1-one O-methyloximes and 3-arylprop-2-yn-1-(2-methoxyphenyl)-1-ones resulted in regioselective formation of functionalized isoxazoles and chromones, respectively. Alkoxy(aryl)methyl group containing compounds were obtained in good and high yields.

Key words

isoxazoles - chromones - electrophile-mediated cyclization - oxocarbenium ion

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