Thromboembolism Following Prothrombin Complex Concentrates and Major Surgery in Severe liver Disease

Thromb Haemost 1978; 39(03): 787-788
DOI: 10.1055/s-0038-1646761

Letters to the Editor

Schattauer GmbH Stuttgart

Thromboembolism Following Prothrombin Complex Concentrates and Major Surgery in Severe liver Disease^[*]

A Marassi

Department of Surgery, University Hospital, Via Sforza 35, Milano

Hemophilia and Thrombosis Centre, University Hospital, Via Pace 15, Milano, Italy

,

V Manzullo

Department of Surgery, University Hospital, Via Sforza 35, Milano

Hemophilia and Thrombosis Centre, University Hospital, Via Pace 15, Milano, Italy

,

V di Carlo

Department of Surgery, University Hospital, Via Sforza 35, Milano

Hemophilia and Thrombosis Centre, University Hospital, Via Pace 15, Milano, Italy

,

P M Mannucci

Department of Surgery, University Hospital, Via Sforza 35, Milano

Hemophilia and Thrombosis Centre, University Hospital, Via Pace 15, Milano, Italy

Reference
1 Mannucci PM, Franchi F, Dioguardi N. 1976; Correction of abnormal coagulation in chronic liver disease by combined use of fresh-frozen plasma and prothrombin complex concentrates. Lancet 2: 542
2 Preston FE, Malia RG, Lilleman JS, Blackburn EK. 1977; Heparinized clotting factor concentrates in patients with Christmas disease and liver disease. Thrombosis and Haemostasis 38: 504