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DOI: 10.1055/s-0039-1681564
INFLUENCE OF BOWEL PREPARATION (BP) QUALITY ON THE DETECTION OF SERRATED POLYPS (SP): A PROSPECTIVE STUDY IN A REGIONAL FOBT-BASED COLORECTAL CANCER SCREENING PROGRAM
Publication History
Publication Date:
18 March 2019 (online)
Aims:
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To determine the influence of BP quality on the serrated polyp detection rate (SPDR);
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to describe the proportion of serrated lesions detected in second examinations performed after a poor-prepared initial screening colonoscopy.
Methods:
Prospective study in which all individuals referred for a screening colonoscopy after a positive FOBT between April 2017 and October 2018 were included. Only complete colonoscopies were considered. Six endoscopists and 3 pathologists participed. The Boston BP scale was used (0 – 5 = inadequate; 6 – 7 adequate; 8 – 9 good). The main outcome was SPDR. Secondary outcomes were ADR, advanced adenoma detection rates (AADR) and proximal SPDR.
Results:
In 718 of 750 patients (95.7%) cecum was intubated [women 334 (46,5%); mean (SD) age: 61.6 (5.8)]. A total of 2118 lesions were detected [1368 (64.6%) adenomas and 107 (5.0%) SP]. Overall SPDR was 10.3% (IC95% 10.3 – 15.3) while overall ADR was 67.3% (IC95% 63.5 – 71.0). The relationship of BP with SPDR and ADR is summarized in Tab. 1.
Bowel prep |
ADR (%) |
SPDR (%) |
AADR (%) |
SPDR-PC (%) |
Adequate |
68.6* |
10.0 |
29.4* |
5.6 |
Non-adequate |
58.5 |
13.0 |
17.6 |
4.6 |
Boston≥2 every segment |
69.0* |
10.0 |
29.7* |
5.8 |
Boston < 2 any segment |
58.8 |
12.6 |
17.5 |
4.1 |
No relationship between SPDR and BP adjusted for age, sex, withdrawal time anendoscopist was found. Forty-four (54.3%) of the 81 reexaminations were because of poor BP. SPDR and ADR in these colonoscopies was 6.8% (IC95% 4.8 – 8.8) and 68.2% (IC95% 64.3 – 71.7) respectively. Presence of a SP in the initial endoscopy did not predict a SP in the reexamination.
Conclusions:
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Unlike ADR and AADR, SPDR is not influenced by BP.
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SPDR in reexaminations is similar to that of the initial colonoscopies.
A different approach to reexaminations depending on the initial findings is not warranted.