Adipositas - Ursachen, Folgeerkrankungen, Therapie 2021; 15(03): 150
DOI: 10.1055/s-0041-1735670
Abstracts
Wiesbaden: Adipositas-Kongress 2021

5 Weight-Loss Maintenance with Once-Weekly Semaglutide 2.4 mg in Adults with Overweight or Obesity Reaching Maintenance Dose (STEP 4)

Domenica Rubino
1   Washington Center for Weight Management, Arlington, USA
,
Niclas Abrahamsson
2   Uppsala University, Uppsala, Schweden
,
Melanie Davies
3   University of Leicester, Leicester, Vereinigtes Königreich
,
Dan Hesse
4   Novo Nordisk, Soborg, Dänemark
,
Frank Greenway
5   Louisiana State University System, Baton Rouge, USA
,
Camilla Jensen
4   Novo Nordisk, Soborg, Dänemark
,
Ildiko Lingvay
6   Southwestern Medical Center, Dallas, USA
,
Tanja Wiedenmann
7   Novo Nordisk, Mainz, Deutschland
,
Ofri Mosenzon
8   Hebrew University of Jerusalem, Jerusalem, Israel
,
Julio Rosenstock
9   Dallas Diabetes Research Center at Medical City, Dallas, USA
,
Miguel Rubio
10   Hospital Clínico Universitario San Carlos and Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spanien
,
Gottfried Rudolfsky
11   Cantonal Hospital, Olten, Schweiz
,
Sayeh Tadayon
4   Novo Nordisk, Soborg, Dänemark
,
Thomas Wadden
12   University of Pennsylvania, Philadelphia, USA
,
Dror Dicker
13   Tel Aviv University, Tel Aviv, Israel
› Author Affiliations
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Zusammenfassung

In adults with overweight or obesity, continued treatment with OW s.c. semaglutide 2.4 mg led to clinically relevant weight loss, while switching to placebo led to significant weight regain; these data underscore the chronicity and relapsing nature of obesity, and the need for continued treatment.



Publication History

Article published online:
24 September 2021

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