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DOI: 10.1055/s-0044-1788005
Advanced Anal Carcinoma during Pregnancy: A Case Report
Funding The authors declare that they have not received financial support from agencies in the public, private, or non-profit sectors to conduct the present study.
Abstract
Objective To present a rare case of anal squamous cell carcinoma (SCC) in a young pregnant woman.
Material and Methods The information was collected based on the clinical record after obtaining the informed consent of the patient.
Results This is the case of a 34-year-old pregnant woman with stage IIIB anal SCC. She was treated with chemotherapy before delivery, followed by cesarean section and chemoradiotherapy after birth. The patient experienced complete clinical and imaging regression after treatment, but she presented early tumor regrowth requiring abdominoperineal amputation, with negative surgical margins.
Discussion The treatment of anal cancer in pregnant women is based on a multidisciplinary approach, adapting current clinical guidelines. It establishes a challenge from an ethical point of view that must consider the impact on the health of the mother and the fetus. Anal screening in carriers of cervical pathology due to papilloma virus would be a good tool for early detection.
Keywords
anal cancer - pregnancy - squamous cell carcinoma - cervical dysplasia - papillomavirus infectionAuthors' Contributions
DAP, conceptualization, data curation, methodology, project administration, formal analysis, research, visualization, and writing - review and editing; JAP, conceptualization, data curation, project administration, research, visualization, and writing - review and editing; ARV, conceptualization, validation, supervision, research, and resources; GCV, conceptualization, validation, methodology, supervision, research, resources, visualization, writing - review and editing.
Publication History
Received: 31 August 2023
Accepted: 09 April 2024
Article published online:
04 September 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
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