Synthesis 1986; 1986(7): 535-538
DOI: 10.1055/s-1986-31694
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

3-Nitropropanal and 3-Nitropropanol: Preparation of the Parent Compounds and Derivatives

Reinhold Öhrlein* , Wilfried Schwab, Rudolf Ehrler, Volker Jäger
  • *Institut für Organische Chemie der Universität, Am Hubland, D-8700 Würzburg, Federal Republic of Germany
Further Information

Publication History

Publication Date:
20 August 2002 (online)

3-Nitropropanal has been prepared for the first time by 1,4-nitrite addition to acrolein. Several acetals of 3-nitropropanal are described, as well as 3-nitropropanal and some of its ethers. 3-Nitropropanal has been obtained by borane-dimethyl sulfide reduction of both 3-nitropropanal and 3-nitropropanoic acid. These reactions make available a variety of nitro compounds known as, or expected to become, highly useful and versatile building blocks for organic syntheses.