Synthesis 2000; 2000(11): 1532-1534
DOI: 10.1055/s-2000-7613
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Aromatization of Hantzsch 1,4-Dihydropyridines with I2-MeOH

Jhillu S. Yadav* , Basi V. Subba Reddy, Gowravaram Sabitha, Garudammagari S. Kiran Kumar Reddy
  • *Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

4-Alkyl or aryl substituted Hantzsch 1,4-dihydropyridines are aromatized to the corresponding pyridines in high yields by iodine in refluxing methanol. The method tolerates several substituents such as alkyl, benzyl, aryl and heterocyclic groups present in the 4-position of pyridines.

Hantzsch 1,4-dihydropyridines - iodine-MeOH - aromatization