Synthesis 2006(14): 2413-2417  
DOI: 10.1055/s-2006-942449
PAPER
© Georg Thieme Verlag Stuttgart · New York

A Facile Synthesis of 1-Phenylsulfonyl-3-substituted-2-cyanoindoles, 1-Phenylsulfonyl-2-methyl-3-cyanoindoles, and Bifunctional 1-Phenyl­sulfonylindoles

Pichamuthu Jaisankar, P. C. Srinivasan*
Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai-25, India
e-Mail: pancol2000@yahoo.co.in; e-Mail: vjpshankar@yahoo.co.in;
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Publikationsverlauf

Received 2 November 2005
Publikationsdatum:
29. Juni 2006 (online)

Abstract

A facile ‘one-pot’ introduction of the cyano group into the 2/3-position of indole has been developed from the corresponding aldehydes using anhydrous aluminum chloride and sodium azide.