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Planta Med 1997; 63(2): 183-186
DOI: 10.1055/s-2006-957642
DOI: 10.1055/s-2006-957642
Letters
© Georg Thieme Verlag Stuttgart · New York
Cycloartane Triterpene Glycosides from the Roots of Astragalus melanophrurius
Weitere Informationen
Publikationsverlauf
1996
1996
Publikationsdatum:
04. Januar 2007 (online)
Abstract
From the roots of Astragalus melanophrurius eight known saponins (1-8) were isolated. Based on spectral data (IR, 1H- and 13C-NMR, and FABMS), the structures were established as astrasieversianins II (1) and X (4), astragalosides I (2), II (3), IV (5) and VI (7), and cyclocanthosides E (6) and G (8). The isolates were evaluated in a broad range of bioassay systems and found to be inactive. Modest antibacterial activity was observed, however, as was immunomodulatory activity, as indicated by stimulation of isolated human lymphocytes.