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Planta Med 1985; 51(6): 504-507
DOI: 10.1055/s-2007-969576
DOI: 10.1055/s-2007-969576
Research Articles
© Georg Thieme Verlag Stuttgart · New York
The Reversion of Sickled Cells by Cajanus cajan
Further Information
Publication History
1985
1985
Publication Date:
26 February 2007 (online)
Abstract
Boiled and crude ethanolic extracts of edible Cajanus cajan beans were prepared and used for in vitro studies involving 14 individual blood samples obtained from confirmed sickle cell (HbSS) patients. It was demonstrated that the extracts were able not only to inhibit sickling in sodium metabisulphite solution, but also quickly reverted to normal morphology, already sickled erythrocytes. There was also a noticeable improvement in the general morphology of the sickle cell erythrocytes after coming into contact with the plant extracts.