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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2008; 29(04): 31-33
DOI: 10.4103/0971-5851.51405
Case Report

Merkel cell carcinoma of skin

M Janaki
Department of Radiotherapy, M S Ramaiah Medical College, Bangalore - 560054, India
,
Kirthi Koushik
Department of Radiotherapy, M S Ramaiah Medical College, Bangalore - 560054, India
,
Rekha Baby
Department of Radiotherapy, M S Ramaiah Medical College, Bangalore - 560054, India
,
Venkatesh Kempiah
Department of Radiotherapy, M S Ramaiah Medical College, Bangalore - 560054, India
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Abstract

Merkel cell carcinoma is a rare neuroendocrinal tumour of the skin. It is noted for its typical aggressive nature unlike other skin tumours. Because of the rarity, the treatment is not standardised. Radiotherapy in the postoperative setting is effective in improving the loco regional control. A case of merkel cell carcinoma treated with postoperative radiotherapy is reported. Pertinent literature is reviewed.



Publication History

Article published online:
19 November 2021

© 2008. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Vincent.T.Devita, Jr Theodore S Lawrence, Steven.A.Rosenberg: Cancer; Principles and practice of oncology; 8th Edition, 2008:878-1879
  • 2 Nicholson SA, McDermott MB, Swanson PE, Wick MR: CD99 and cytokeratin-20 in small-cell and basaloid tumours of the skin; Appl Immunohistochem Mol Morphol. 2000;8(1):37-41
  • 3 Bichakjian CK, Lowe L, Lao CD, Sandler HM, Bradford CR, Johnson TM, and Wong SL: Merkel cell carcinoma: critical review with guidelines for multidisciplinary management; Cancer 2007;110:1-12.
  • 4 Boyle F, Pendlebury S, Bell D: Further insights into the natural history and management of primary cutaneous neuroendocrine (Merkel cell) carcinoma.. Int J Radiat Oncol Biol Phys. 1995;31(2):315-23
  • 5 Jabbour James, Cumming Robert, Richard A. et. al. Merkel Cell Carcinoma: Assessing the Effect of Wide Local Excision, Lymph Node Dissection, and Radiotherapy on Recurrence and Survival in Early- Stage Disease-Results From a Review of 82 Consecutive Cases Diagnosed Between 1992 and 2004; Ann Surgical Oncology 2007;14:1943-1952.
  • 6 Lewis KG, Weinstock MA, Weaver AL, Otley CC: Adjuvant local irradiation for merkel cell carcinoma; Arch Dermatology, 2006;142(6):693-700
  • 7 Tai PT, Yu E, Winquist E, et. al. Chemotherapy in neuroendocrine/Merkel cell carcinoma of the skin: case series and review of 204 cases; J clin Oncol 2000;18(12):2493-9.