Synfacts 2021; 17(03): 0291
DOI: 10.1055/s-0040-1720317
Metals in Synthesis

Redox-Neutral Manganese-Catalyzed Silylation of Alkenes

Rezensent(en):
Mark Lautens
,
Randy Sanichar
Dong J, Yuan X.-A, Yan Z, Mu L, Ma J, Zhu C, Xie J. * Nanjing University, P. R. of China
Manganese-Catalysed Divergent Silylation of Alkenes.

Nat. Chem. 2021;
13: 182-190
 

Significance

Xie and co-workers report a ­manganese-catalyzed dehydrosilylation and hydrosilylation of alkenes. They have shown that the reaction is easily scalable and affords the silylated product in good yields. The reaction proceeds equally well with both aliphatic and aromatic alkene starting materials.


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Comment

Notably, the reaction is highly selective for the linear silylated product, stemming from the anti-Markovnikov addition of the silyl radical to the alkene. Additionally, under the specific conditions, either the dehydrosilylation or hydrosilylation product can be accessed with excellent selectivity.


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Publikationsverlauf

Artikel online veröffentlicht:
16. Februar 2021

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