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DOI: 10.1055/s-2002-35213
Low-Grade Myofibroblastic Sarcoma of the Chest Wall: A Rare Tumor Entity
Niedrigmalignes myofibroblastisches Sarkom der Thoraxwand: Eine seltene TumorentitätPublication History
Publication Date:
31 October 2002 (online)
![](https://www.thieme-connect.de/media/tumor/200205/lookinside/thumbnails/10.1055-s-2002-35213-1.jpg)
Abstract
Low-grade myofibroblastic sarcoma of the chest wall is a rare tumor entity. We report a case in a 58-year-old patient in whom en-bloc resection of the tumor and reconstruction of the chest wall was performed. Initially no further adjuvant treatment was established. Due to recurrence, the patient underwent resection of the lower chest-/upper abdominal wall and pericardial resection. Low-grade myofibroblastic sarcoma arise from myofibroblasts, which have ultrastructural and physiological features of both fibroblasts and smooth muscle cells. Even though metastatic spread seems to be seldom, there is great tendency for local recurrence.
Key words
Myofibroblastic tumor - Sarcoma - Chest wall tumor
Literatur
- 1 Mentzel T, Dry S, Katenkamp D, Fletcher C D. Low-grade myofibroblastic sarcoma: analysis of 18 cases in the spectrum of myofibroblastic tumors. Am J Surg Pathol. 1998; 22 1228-1238
- 2 Eyden B P, Banerjee S S, Harris M, Mene A. A study of spindle cell sarcomas showing myofibroblastic differentiation. Ultrastruct Pathol. 1991; 15 367-378
- 3 Bisceglia M, Magro G. Low-grade myofibroblastic sarcoma of the salivary gland. Am J Surg Pathol. 1999; 23 1435-1436
- 4 Majno G, Gabbiani G, Hirschel B J, Ryan G B, Statkov P R. Contraction of granulation tissue in vitro: similarity to smooth muscle. Science. 1971; 173 548-550
- 5 Gabbiani G, Ryan G B, Mayne G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia. 1971; 27 549-550
- 6 Schürch W, Seemayer T A, Gabbiani G. The myofibroblast: a quarter century after its discovery. Am J Surg Pathol. 1998; 22 141-147
- 7 Watanabe K, Kusakabe T, Hoshi N, Saito A, Suzuki T. h-Caldesmon in leiomyosarcoma and tumors with smooth muscle cell-like differentiation: its specific expression in the smooth muscle cell tumor. Human Pathol. 1999; 30 392-396
- 8 Ceballos K M, Nielsen G P, Selig M K, O'Connell J X. Is anti-h-Caldesmon useful for distinguishing smooth muscle and myofibroblastic tumors? An immunohistochemical study. Am J Clin Pathol. 2000; 114 746-753
Paul Schneider, MD
Dept. of General, Vascular and Thoracic Surgery, Benjamin Franklin Medical Center,
Freie Universität Berlin
Hindenburgdamm 30
12200 Berlin
Phone: + 49-30-8445-2543
Fax: + 49-30-8445-2740
Email: p.schneider@ukbf.fu-berlin.de