Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. - Parlati,F.; Lee,S.J.; Aujay,M.; Suzuki,E.; Levitsky,K.; Lorens,J.B.; Micklem,D.R.; Ruurs,P.; Sylvain,C.; Lu,Y.; Shenk,K.D.; Bennett,M.K. (Blood, 2009)