(untitled) - Sun, Y; Ma, X; Cheng, K; Wu, B; Duan, J; Chen, H; Bu, L; Zhang, R; Hu, X; Deng, Z; Xing, L; Hong, X; Cheng, Z (Angew. Chem. Int. Ed., 2015)
Cheng and colleagues reported that amine base catalysts, e.g. Hünig base, substantially promote thiol addition reactions of cyclooctynes. Thus, we performed a control experiment of 1a with similar conditions to their report: