PGC-1a Deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis - Leone, T C; Lehman, J J; Finck, B N; Schaeffer, P J; Wende, A R; Boudina, S; Courtois, M; Wozniak, D F; Sambandam, N; Bernal-Mizrachi, C; Chen, Z; Holloszy, J O; Medeiros, D M; Schmidt, R E; Saffitz, J E; Abel, E D; Semenkovich, C F; Kelly, D P (PLoS Biol, 2005)