The Asp(272)-Glu(282) region of platelet glycoprotein Ibalpha interacts with the heparin-binding site of alpha-thrombin and protects the enzyme from the heparin-catalyzed inhibition by antithrombin III. - De-Cristofaro,R.; De-Candia,E.; Rutella,S.; Weitz,J.I. (J Biol Chem, 2000)