The catalytic histidine dyad of high density lipoprotein-associated serum paraoxonase-1 (PON1) is essential for PON1-mediated inhibition of low density lipoprotein oxidation and stimulation of macrophage cholesterol efflux. - Rosenblat,M.; Gaidukov,L.; Khersonsky,O.; Vaya,J.; Oren,R.; Tawfik,DS.; Aviram,M. (J Biol Chem, 2006)