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DOI: 10.1055/s-2007-1013594
© Georg Thieme Verlag, Stuttgart · New York
Gigantism Associated with McCune-Albright's Syndrome
Publication History
1983
1984
Publication Date:
14 March 2008 (online)
Summary
The case of a 16 year-old boy with McCune-Albright's syndrome which is rarely accompanied by gigantism was studied endocrinologically.
The stimulation of growth hormone (GH) release by hypoglycemia, the decline of elevated GH by hyperglycemia and a little lower somatostatin like immunoreactivity (SLI) may support abnormalities of hypothalamic function, but the existence of pituitary microadenoma cannot be ruled out because of the paradoxical suppression of GH release by oral administration of bromocriptine (CB-154) and L-DOPA and the stimulation of GH release by intravenous administration of TRH.
Key-Words:
Gigantism - McCune-Albright's Syndrome