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DOI: 10.1055/s-0031-1298157
© Georg Thieme Verlag KG Stuttgart · New York
Bicyclo[4.4.0]decane Oxygenated Sesquiterpenes from Eryngium maritimum Essential Oil
Publication History
received October 24, 2011
revised December 12, 2011
accepted December 14, 2011
Publication Date:
18 January 2012 (online)
Abstract
Investigation of the essential oil of the aerial parts of Eryngium maritimum L. from Corsica led to the isolation of one known sesquiterpene (1) and three new oxygenated sesquiterpenes with a muurolane or cadinane skeleton (2–4). Structure assignments of 4βH-muurol-9-en-15-al (1), 4βH-cadin-9-en-15-al (2), 4βH-muurol-9-en-15-ol (3) and 4βH-cadin-9-en-15-ol (4) were carried out by GC/MS (EI and CI) and comprehensive 1D and 2D NMR spectroscopy. Antibacterial activity of Eryngium maritimum L. oil and column chromatography fractions have been investigated for the first time. The oxygenated fraction, which contains the four sesquiterpenes, was efficient against Listeria monocytogenes and Echerichia coli.
Key words
Eryngium maritimum L. - Apiaceae - essential oil - novel oxygenated sesquiterpenes - 2D NMR - antibacterial activity - bicyclo[4.4.0]decane
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Alain Muselli
UMR CNRS 6134
Laboratoire Chimie des Produits Naturels
Université de Corse
BP 52
20250 Corti
France
Phone: +33 4 95 45 01 71
Fax: +33 4 95 45 01 80
Email: muselli@univ-corse.fr