Synthesis of Aryl Nitriles via Aerobic Oxidative Cleavage of Aryl C=C Bonds with (NH₄)₂CO₃ as the Nitrogen Source

Abstract

An aerobic oxidative method was developed for conversion of arylethenes to aromatic nitriles using (NH₄)₂CO₃ as the nitrogen source and Cu(NO₃)₂ as the catalyst. The present method allowed a series of arylethenes to underwent oxidative cleavage of C=C bonds to give the targeted products in low to high yields. In addition, the present conditions are compatible with many groups such as alkyl, alkoxy, N,N-dimethylamino, chloro, bromo, iodo, ester, cyano group, and so on.

Key words

aromatic nitriles - arylethenes - carbon–carbon double bonds - oxidative cleavage - oxygen

Publication History

Received: 20 November 2021

Accepted after revision: 14 December 2021

Article published online:
18 January 2022

• References and Notes

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