Planta Med 2003; 69(6): 579-582
DOI: 10.1055/s-2003-40635
Letter
© Georg Thieme Verlag Stuttgart · New York

Dissectol A, An Unusual Monoterpene Glycoside from Incarvillea dissectifoliola

Wei Chen1 , Yuemao Shen1 , Jianchu Xu1
  • 1Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, P. R. China
Further Information

Publication History

Received: October 24, 2002

Accepted: February 15, 2003

Publication Date:
16 July 2003 (online)

Abstract

An unusual monoterpene glycoside named dissectol A (1) was isolated from the EtOH extract of Incarvillea dissectifoliola, and its structure was determined by 1D and 2D NMR data. The antimicrobial bioassays showed that dissectol A had modest inhibitory activity against Mycobacterium tuberculosis when compared to rifampicin in an agar diffusion assay.

References

  • 1 Li G -D. Research on ”Wabuyou” (an Yi medicine).  Chin Herb Med (Zhongcaoyao). 1986;  17 272-3
  • 2 Wang X, Cui J -R, Xiao Z -P, Zhang Y -H, Li C -L, Zhao Y -Y,. et al . Comparative studies of Chinese drug Tongucao on anti-inflammatory and analgesic effects.  J Beijing Med Univ. 1998;  30 145-68
  • 3 Yang M -K, Tang Y -S, Cai L -M. Research on constituents of Incarvillea arguta (”matonghua¿).  Acta Pharm Sin. 1987;  22 711-6
  • 4 Chi Y -M, Yan W -M, Li J -S. An alkaloid from Incarvillea sinensis .  Phytochemistry. 1990;  29 2376-8
  • 5 Chi Y -M, Yan W -M, Chen D -C, Noguchi H, Iitaka Y. A monoterpene alkaloid from Incarvillea sinensis .  Phytochemistry. 1992;  31 2930-2
  • 6 Chi Y -M, Hashimoto F, Yan W -M, Nohara T. Incarvine A, a monoterpene alkaloid from Incarvillea sinensis .  Phytochemistry. 1995;  40 353-4
  • 7 Chi Y -M, Hashimoto F, Yan W -M, Nohara T. Two alkaloids from Incarvillea sinensis .  Phytochemistry. 1995;  39 1485-7
  • 8 Chi Y -M, Hashimoto F, Yan W -M, Nohara T. Four monoterpene alkaloid derivatives from Incarvillea sinensis .  Phytochemistry. 1997;  46 763-9
  • 9 Nakamura M, Chi Y -M, Kinjo J, Yan W -M, Nohara T. Two monoterpene alkaloidal derivatives from Incarvillea sinensis .  Phytochemistry. 1999;  51 595-7
  • 10 Chi Y -M, Hashimoto F, Yan W -M, Nohara T. Five novel macrocyclic spermine alkaloids from Incarvillea sinensis .  Tetrahedron Lett. 1997;  38 2713-6
  • 11 Nakamura M, Kido K, Kinjo J, Nohara T. Antinociceptive substances from Incarvillea delavayi .  Phytochemistry. 2000;  53 253-6
  • 12 Nakamura M, Kido K, Kinjo J, Nohara T. Two novel actinidine-type monoterpene alkaloids from Incarvillea delavayi .  Chem Pharm Bull. 2000;  48 1826-7
  • 13 Nakamura M, Chi Y -M, Yan W -M, Yonezawa A, Nakasugi Y, Yoshizawa T,. et al . Structure-antinociceptive activity studies of Incarvillateine, a monoterpene alkaloid from Incarvillea sinensis .  Planta Med. 2001;  67 114-7
  • 14 Zhao Q -S. A new species of Incarvillea (Bignoniaceae) from Sichuan.  Acta Phytotaxonom Sin. 1988;  26 78-9
  • 15 Jorgensen J H, Turnidge J D, Washington J A. Antibacterial Susceptibility Tests: Dilution and Disk Diffusion Methods. In: Manual of Clinical Microbiology. 7th Edn (Murray PR editor) pp. 1526-43 American So ciety for Microbiology Washington DC; 1999

Yuemao Shen

The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany

Chinese Academy of Sciences

Heilongtan

Kunming

Yunnan 650204

People′s Republic of China

Phone: +86-871-5223111

Fax: +86-871-5150227

Email: yshen@public.km.yn.cn

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