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Thromb Haemost 1970; 23(02): 340-346
DOI: 10.1055/s-0038-1654146
Originalarbeiten – Original Articles – Travaux Originaux
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Congenital Hemorrhagic Diathesis with Deficiency of Factor XIII

A Case Report and a Family Study
J Abels M.D.,   *
1   Division of Hematology, Department of Medicine, University of Groningen, Groningen, The Netherlands
,
C. Th Smit Sibinga M.D.
1   Division of Hematology, Department of Medicine, University of Groningen, Groningen, The Netherlands
,
L Meyleb M.D.
1   Division of Hematology, Department of Medicine, University of Groningen, Groningen, The Netherlands
› Author Affiliations
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Publication History

Publication Date:
27 June 2018 (online)

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Summary

A male patient with a severe congenital bleeding disorder due to factor XIII deficiency is described. An extensive family study revealed no additional demonstrable deficiencies of this factor. A lowered fibrinogen level in four of the father’s relatives was found, and remained unexplained. Prophylactic treatment with plasma transfusions appeared to be effective.

* Present address : Department of Medicine, University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706 USA.


 

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