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Synthesis 1988; 1988(12): 963-966
DOI: 10.1055/s-1988-27767
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Synthesis of Verruculotoxin

Robert M. Williams* , Eduard J. Brunner, Mark R. Sabol
  • *Departrnent of Chemistry, Colorado State University, Fort Collins, CO 80523, USA
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Publication History

Publication Date:
20 August 2002 (online)

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The mycotoxic alkaloid verruculotoxin (2) has been synthesized from (S)-phenylalanine and pipecolinic acid. A selective method to reduce a dioxopiperazine to an oxopiperazine is described.